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Binnen de ruime keuze aan mogelijkheden die beschikbaar zijn voor diagnostisch onderzoek, neemt het laboratoriumonderzoek een prominente plaats in. Een lacune in de Nederlandstalige informatie over deze onderzoeksvorm werd in 2009 opgevuld door de eerste druk van het Handboek medische laboratoriumdiagnostiek. Deze uitgave groeide uit tot een standaardwerk en kreeg een bestsellerstatus.Nu is de lang verwachte tweede, geheel herziene druk beschikbaar. Nieuwe tests zijn toegevoegd, oude, minder toegepaste tests zijn verwijderd en de inhoud is volledig geactualiseerd. Het handboek verschijnt met ingang van deze tweede druk volledig in kleur waardoor de vele toegevoegde illustraties prachtig tot hun recht komen. 

Het handboek biedt een heldere en praktijkgerichte inleiding op zinvol laboratoriumonderzoek en een uitgebreid overzicht van beschikbare tests. De ruim 450 tests worden gestructureerd beschreven naar doel, benodigde klinische informatie, beschrijving van de testmethode, mogelijke toepassingen en interpretatie. Natuurlijk ontbreken daarbij de referentiewaarden niet.

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A. Harichandan K. Sivasubramaniyan H.-J. Bühring Prospective Isolation and Characterization of Human Bone Marrow-Derived MSCs Christina Benda Ting Zhou Xianming Wang Weihua Tian Johannes Grillari Hung-Fat Tse Regina Grillari-Voglauer Duanqing Pei Miguel A. Esteban Urine as a Source of Stem Cells Sven Kinzebach Karen Bieback Expansion of Mesenchymal Stem/Stromal Cells under Xenogenic-Free Culture Conditions Danielle Minteer Kacey G Marra J Peter Rubin Adipose-Derived Mesenchymal Stem Cells: Biology and Potential Applications Antonina Lavrentieva Tim Hatlapatka Anne Neumann Birgit Weyand Cornelia Kasper Potential for Osteogenic and Chondrogenic Differentiation of MSC Letizia Ferroni Chiara Gardin Ilaria Tocco Roberta Epis Alessandro Casadei Vincenzo Vindigni Giuseppe Mucci Barbara Zavan Potential for Neural Differentiation of Mesenchymal Stem Cells Thomas Dittmar Frank Entschladen Migratory Properties of Mesenchymal Stem Cells Stefania Bruno Federica Collino, Ciro Tetta Giovanni Camussi Dissecting Paracrine Effectors for Mesenchymal Stem Cells Yin Xiao Jiezhong Chen Proteomics Approaches in the Identification of Molecular Signatures of Mesenchymal Stem Cells Richard Schäfer Does the Adult Stroma Contain Stem Cells?

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Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists.  Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.

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